Nolvadex (Tamoxifen citrate)

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Nolvadex is the trade name of a drug containing a molecule called Tamoxifen. Its primary use by male bodybuilders is to prevent gynecomastia (the growth of the breast tissue). It was introduced by steroid guru Dan Duchaine 25 years ago. After a quarter of century, it is time for an update about its use. What I am going to demonstrate is it is high time to eliminate Nolvadex from the bodybuilder's drug stacks.

Nolvadex also shows the ability to increase production of FSH (follicle stimulating hormone) and LH (luteinizing hormone) in the male body. This property is accomplished by blocking negative feedback inhibition caused by estrogen at the hypothalamus and pituitary, which fosters the release of the mentioned pituitary hormones. This property of course is also the function of Clomid and cyclofenil. Since a higher release of LH can stimulate the Leydig's cells in the testes to produce more testosterone, Nolvadex can have a positive impact on one's serum testosterone level. This "testosterone stimulating" effect of Nolvadex is an added benefit when preparing to conclude a steroid cycle. Since most anabolic/androgenic steroids will suppress endogenous testosterone production, Nolvadex can help restore a balance in hormone levels. Nolvadex should be preferred over Clomid for this purpose in fact, as side by side it is clearly the stronger agent. It has also been shown to increase LH responsiveness to Gonadotropin Releasing Hormone after time, while Clomid slightly lowers this sensitivity as the drug is used for several weeks.

Nolvadex is a trade name for the drug tamoxifen citrate. Nolvadex is a trade name for the drug tamoxifen citrate. Nolvadex is a non-steroidal agent that demonstrates potent antiestrogenic properties. Nolvadex is effective against estrogen. Nolvadex is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an antiestrogenic effect of Nolvadex is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of Nolvadex to block its action in such cells has proven to be a very effective treatment. Nolvadex is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While it is effective against estrogen, it is not our strongest available remedy. We now have the drug Arimidex available to us, which notably prevents estrogen from being manufactured in the first place. Nolvadex is useful against estrogen. Altering the effect of estrogen in the female body can cause a level of discomfort, so antiestrogens are most bearable when used after the point of menopause. Since Nolvadex is milder in comparison, that is more widely applicable and usually the first treatment option.
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